1.He is good at English， _______ we all know.
A. that B. as C. whom D. what
2.The pen _______ he is writing is mine.
A. with which B. in which C. on which D. by which
3.Do you know the year _______ the Chinese Communist Party was founded?
A. which B. that C. when D. on which
4.The place _______ interested me most was the Children‘s Palace.
A. which B. where C. what D. in which
5._____ she was very tired， she went on working.
A. As B. Although C. Even D. In spite of考试吧
2.正确答案：A答案解析：with which是“介词+关系代词”结构，常用来引导定语从句。with有“用”的意思，介词之后只能用which，不能用that. with which在定语从句中作状语，即he is writing with a pen.